Amyloid fibril (in vitro) from full-length hnRNPA1 protein
Resolution: 3.32 Å
EM Method: Helical reconstruction
Fitted PDBs: 7zj2
Q-score: 0.491
Sharma K, Banerjee S, Savran D, Rajes C, Wiese S, Girdhar A, Schwierz N, Lee C, Shorter J, Schmidt M, Guo L, Fandrich M
J Mol Biol (2023) 435 pp. 168211-168211 [ Pubmed: 37481159 DOI: doi:10.1016/j.jmb.2023.168211 ]
virus enhancing amyloid fibril formed by CKFKFQF
Resolution: 2.86 Å
EM Method: Helical reconstruction
Fitted PDBs: 8okr
Q-score: 0.508
Heerde T, Schutz D, Lin YJ, Munch J, Schmidt M, Fandrich M
Nat Commun (2023) 14 pp. 4293-4293 [ DOI: doi:10.1038/s41467-023-40042-1 Pubmed: 37464004 ]
- Virus enhancing amyloid (Complex from synthetic construct)
- Pnf-18 (949 Da, Protein from HIV whole-genome vector AA1305#18)
Infectious mouse-adapted ME7 scrapie prion fibril purified from terminally-infected mouse brains
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8a00
Q-score: 0.633
Manka SW, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF
Nat Chem Biol (2023) 19 pp. 607-613 [ DOI: doi:10.1038/s41589-022-01229-7 Pubmed: 36646960 ]
- Major prion protein (15 kDa, Protein from house mouse)
- Amyloid fibril of prion protein (Complex from Mus musculus)
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8efu
Q-score: 0.462
Hoyt F, Alam P, Artikis E, Schwartz CL, Hughson AG, Race B, Baune C, Raymond GJ, Baron GS, Kraus A, Caughey B
PLoS Pathog (2022) 18 pp. e1010947-e1010947 [ DOI: doi:10.1371/journal.ppat.1010947 Pubmed: 36342968 ]
- Gpi anchorless underglycosylated 22l prion fibril (Complex from Mus musculus)
- Major prion protein (25 kDa, Protein from house mouse)
Infectious mouse-adapted RML scrapie prion fibril purified from terminally-infected mouse brains
Resolution: 2.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 7qig
Q-score: 0.632
Manka SW, Zhang W, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF
Nat Commun (2022) 13 pp. 4004-4004 [ DOI: doi:10.1038/s41467-022-30457-7 Pubmed: 35831275 ]
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7td6
Q-score: 0.501
Hoyt F, Standke HG, Artikis E, Schwartz CL, Hansen B, Li K, Hughson AG, Manca M, Thomas OR, Raymond GJ, Race B, Baron GS, Caughey B, Kraus A
Nat Commun (2022) 13 pp. 4005-4005 [ Pubmed: 35831291 DOI: doi:10.1038/s41467-022-30458-6 ]
- Arml prion (Complex from Mus musculus)
- Major prion protein (28 kDa, Protein from house mouse)
Mamchur AA, Moiseenko AV, Panina IS, Yaroshevich IA, Kudryavtseva SS, Pichkur EB, Sokolova OS, Muronetz VI, Stanishneva-Konovalova TB
Biomedicines (2021) 9 [ DOI: doi:10.3390/biomedicines9111649 Pubmed: 34829878 ]
- Prion protein (Protein from Ovis aries)
- Prion protein (Complex from Ovis aries)
- Groel (Complex from Escherichia coli K-12)
- Groel (Protein from Escherichia coli K-12)
- Complex of groel with prion protein (Complex)
Cryo-EM structure of amyloid fibril formed by familial prion disease-related mutation E196K
Resolution: 3.07 Å
EM Method: Helical reconstruction
Fitted PDBs: 7dwv
Q-score: 0.483
Infectious mammalian prion fibril (263K scrapie)
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 7lna
Q-score: 0.559
Kraus A, Hoyt F, Schwartz CL, Hansen B, Artikis E, Hughson AG, Raymond GJ, Race B, Baron GS, Caughey B
Mol Cell (2021) 81 pp. 4540- [ Pubmed: 34433091 DOI: doi:10.1016/j.molcel.2021.08.011 ]
Cryo-EM structure of amyloid fibril formed by full-length human prion protein
Resolution: 2.702 Å
EM Method: Helical reconstruction
Fitted PDBs: 6lni
Q-score: 0.606
Wang LQ, Zhao K, Yuan HY, Wang Q, Guan Z, Tao J, Li XN, Sun Y, Yi CW, Chen J, Li D, Zhang D, Yin P, Liu C, Liang Y
Nat Struct Mol Biol (2020) 27 pp. 598-602 [ DOI: doi:10.1038/s41594-020-0441-5 Pubmed: 32514176 ]
- Major prion protein (22 kDa, Protein from Homo sapiens)
- Human prion protein amyloid fibril (Cellular component from Homo sapiens)